Vyvanse 60 mg (Lisdexamfetamine Dimesylate) – ADHD
VYVANSE 60 mg (lisdexamfetamine dimesylate), a CNS stimulant, is for once-a-day oral administration. The chemical designation for lisdexamfetamine dimesylate is (2S)-2,6-diaminoN-[(1S)-1-methyl-2-phenylethyl] hexanamide dimethanesulfonate. The molecular formula is C15H25N3O•(CH4O3S)2, which corresponds to a molecular weight of 455.60.
VYVANSE (lisdexamfetamine dimesylate) Structural Formula Illustration
Lisdexamfetamine dimesylate is a white to off-white powder that is soluble in water (792 mg/mL).
Information for VYVANSE Capsules
VYVANSE capsules contain 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, and 70 mg of lisdexamfetamine dimesylate (equivalent to 5.8 mg, 11.6 mg, 17.3 mg, 23.1 mg, 28.9 mg, 34.7 mg, and 40.5 mg of lisdexamfetamine).
Inactive ingredients: microcrystalline cellulose, croscarmellose sodium, and magnesium stearate. The capsule shells contain gelatin, titanium dioxide, and one or more of the following: FD&C Red #3, FD&C Yellow #6, FD&C Blue #1, Black Iron Oxide, and Yellow Iron Oxide.
Information for VYVANSE Chewable Tablets
VYVANSE chewable tablets contain 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, and 60 mg of lisdexamfetamine dimesylate (equivalent to 5.8 mg, 11.6 mg, 17.3 mg, 23.1 mg, 28.9 mg, and 34.7 mg of lisdexamfetamine).
Inactive ingredients: colloidal silicon dioxide, croscarmellose sodium, guar gum, magnesium stearate, mannitol, microcrystalline cellulose, sucralose, artificial strawberry flavor.
VYVANSE® is indicated for the treatment of:
Attention Deficit Hyperactivity Disorder (ADHD) [see Clinical Studies]
Moderate to Severe Binge Eating Disorder (BED) in adults [see Clinical Studies].
Limitation Of Use
VYVANSE is not indicated or recommended for weight loss. Use of other sympathomimetic drugs for weight loss has been associated with serious cardiovascular adverse events. The safety and effectiveness of VYVANSE for the treatment of obesity have not been established [see WARNINGS AND PRECAUTIONS].
Dosage For Treatment Of ADHD
The recommended starting dose is 30 mg once daily in the morning in patients ages 6 and above. Dosage may be adjusted in increments of 10 mg or 20 mg at approximately weekly intervals up to a maximum dose of 70 mg/day
Information For VYVANSE Capsules:
- Capsules 10 mg: pink body/pink cap (imprinted with S489 and 10 mg)
- Capsules 20 mg: ivory body/ivory cap (imprinted with S489 and 20 mg)
- Capsules 30 mg: white body/orange cap (imprinted with S489 and 30 mg)
- Capsules 40 mg: white body/blue-green cap (imprinted with S489 and 40 mg)
- Capsules 50 mg: white body/blue cap (imprinted with S489 and 50 mg)
- Capsules 60 mg: aqua blue body/aqua blue cap (imprinted with S489 and 60 mg)
- Capsules 70 mg: blue body/orange cap (imprinted with S489 and 70 mg)
Information For VYVANSE Chewable Tablets:
- Chewable tablets 10 mg: White to off-white round-shaped tablet debossed with ‘10’ on one side and ‘S489’ on the other
- Chewable tablets 20 mg: White to off-white hexagonal-shaped tablet debossed with ‘20’ on one side and ‘S489’ on the other
- Chewable tablets 30 mg: White to off-white arc triangular-shaped tablet debossed with ‘30’ on one side and ‘S489’ on the other
- Chewable tablets 40 mg: White to off-white capsule-shaped tablet debossed with ‘40’ on one side and ‘S489’ on the other
- Chewable tablets 50 mg: White to off-white arc square-shaped tablet debossed with ‘50’ on one side and ‘S489’ on the other
- Chewable tablets 60 mg: White to off-white arc diamond-shaped tablet debossed with ‘60’ on one side and ‘S489’ on the other
Storage And Handling
Dispense in a tight, light-resistant container as defined in the USP.
Store at room temperature, 20°C to 25° C (68°F to 77° F). Excursions permitted between 15°C and 30° C (59 to 86° F) [see USP Controlled Room Temperature].
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